The United States President’s Malaria Initiative through the United States Agency for International Development (USAID) and managed by Management Sciences for Health (MSH) with NIFAA as a sub-recipient is a five-year project that addresses Malaria in Nigeria. Currently, NIFAA is implementing two task orders under the PMI-S project. This project will contribute to the vision of Nigeria’s National Malaria Elimination Program of having “a malaria-free Nigeria”, and the PMI 2015–2020 goal of reducing malaria-associated mortality by reducing the incidence of severe malaria and associated complications. The goal of PMI-S is to contribute to the reduction of all causes of under-five and maternal mortality by delivering quality services for the management of malaria and its complications and the prevention of malaria during pregnancy. NIFAA’s roles under PMI-S/USAID/MSH are structured around advocacy to the state government to increase funding for malaria activities across the eight states and in collaboration with other consortium partners, push for domestic resource mobilization.